[Food sensitivities of the digestive tract-Part 2: Food intolerances].

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  • Author(s): Bischoff SC;Bischoff SC
  • Source:
    Der Internist [Internist (Berl)] 2022 Mar; Vol. 63 (3), pp. 281-290. Date of Electronic Publication: 2022 Feb 09.
  • Publication Type:
    Journal Article
  • Language:
    German
  • Additional Information
    • Transliterated Title:
      Nahrungsmittelunverträglichkeiten des Verdauungstraktes – Teil 2: Nahrungsmittelintoleranzen.
    • Source:
      Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0264620 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1289 (Electronic) Linking ISSN: 00209554 NLM ISO Abbreviation: Internist (Berl) Subsets: MEDLINE
    • Publication Information:
      Original Publication: Berlin, New York, Springer-Verlag.
    • Subject Terms:
    • Abstract:
      Adverse reactions to food affect about one third of the population. They are based on very different mechanisms and are triggered by specific foods. They are divided into food intolerances, which manifest mainly in the gastrointestinal tract and food allergies, which can also cause extraintestinal symptoms and have an immunological genesis. In adults, food intolerances are significantly more common than food allergies with a prevalence of approximately 10-20%. The most important food intolerances are sugar intolerances, such as lactose and fructose intolerance but intolerances to wheat also play an increasing role. The diagnostics of food intolerances require extensive exclusion diagnostics, whereby in particular irritable bowel syndrome and intestinal dysbiosis must be differentiated. The therapy of food intolerance is primarily based on a targeted elimination diet. In this advanced education article the most important food intolerances are discussed.
      (© 2022. The Author(s).)
    • References:
      Bischoff SC (2019) Laktoseintoleranz. Fruktoseintoleranz. Andere Kohlenhydratintoleranzen. In: Riemann JF, Fischbach W, Galle PR, Mössner J (Hrsg) Referenz Gastroenterologie. Thieme, Stuttgart, S 431–442.
      Comas-Basté O, Sánchez-Pérez S, Veciana-Nogués MT, Latorre-Moratalla M, Vidal-Carou MDC (2020) Histamine intolerance: the current state of the art. Biomolecules 10:1181. (PMID: 10.3390/biom10081181)
      Raithel M, Weidenhiller M, Hagel AFK, Hetterich U, Neurath MF, Konturek PC (2013) The malabsorption of commonly occurring mono and disaccharides: levels of investigation and differential diagnoses. Dtsch Arztebl Int 110:775–782. (PMID: 243008253855820)
      Bischoff SC, Zimmermann J (2018) Weizenunverträglichkeiten – Hype oder Herausforderung? Aktuel Ernahrungsmed 43:459–466. (PMID: 10.1055/a-0754-4973)
      Leitner R, Zoernpfenning E, Missbichler A (2014) Evaluation of the inhibitory effect of various drugs/active ingredients on the activity of human diamine oxidase in vitro. Clin Transl Allergy 4(Suppl 3):P23. https://doi.org/10.1186/2045-7022-4-S3-P23. (PMID: 10.1186/2045-7022-4-S3-P234127955)
      Canani BR, Pezzella V, Amoroso A, Cozzolino T, Di Scala C, Passariello A (2016) Diagnosing and treating intolerance to carbohydrates in children. Nutrients 8:157. (PMID: 10.3390/nu8030157)
      Beyerlein L, Pohl D, Delco F et al (2008) Correlation between symptoms developed after the oral ingestion of 50 g lactose and results of hydrogen breath testing for lactose intolerance. Aliment Pharmacol Ther 27:659–665. (PMID: 10.1111/j.1365-2036.2008.03623.x)
      Corgneau M, Scher J, Ritie-Pertusa L et al (2017) Recent advances on lactose intolerance: Tolerance thresholds and currently available answers. Crit Rev Food Sci Nutr 57:3344–3356. (PMID: 10.1080/10408398.2015.1123671)
      Oak SJ, Jha R (2019) The effects of probiotics in lactose intolerance: a systematic review. Crit Rev Food Sci Nutr 59:1675–1683. (PMID: 10.1080/10408398.2018.1425977)
      Cappello G, Marzio L (2005) Rifaximin in patients with lactose intolerance. Dig Liver Dis 37:316–319. (PMID: 10.1016/j.dld.2004.12.007)
      Tsampalieros A, Beauchamp J, Boland M, Mack DR (2008) Dietary fructose intolerance in children and adolescents. Arch Dis Child 93:1078. (PMID: 10.1136/adc.2008.137521)
      Marcason W (2010) Is medical nutrition therapy (MNT) the same for hereditary vs dietary fructose intolerance? J Am Diet Assoc 110:1128. (PMID: 10.1016/j.jada.2010.05.016)
      Wilder-Smith CH, Olesen SS, Materna A, Drewes AM (2017) Predictors of response to a low-FODMAP diet in patients with functional gastrointestinal disorders and lactose or fructose intolerance. Aliment Pharmacol Ther 45:1094–1106. (PMID: 10.1111/apt.13978)
    • Contributed Indexing:
      Keywords: Elimination diet; Food hypersensitivity; Histamine intolerance; Lactose intolerance; Non-celiac wheat sensitivity
      Local Abstract: [Publisher, German] Nahrungsmittelunverträglichkeiten (NMU) betreffen etwa ein Drittel der Bevölkerung. Sie werden durch umschriebene Nahrungsmittel ausgelöst, wobei sehr unterschiedliche Mechanismen zugrunde liegen. NMU werden unterteilt in Nahrungsmittelintoleranzen (NMI), die sich vor allem im Gastrointestinaltrakt manifestieren, und Nahrungsmittelallergien (NMA), die auch extraintestinal Symptome hervorrufen können und eine immunologische Genese haben. Bei Erwachsenen sind NMI mit einer Prävalenz von etwa 10–20 % deutlich häufiger als NMA. Die wichtigsten NMI sind Zuckerintoleranzen wie Laktose- und Fruktoseintoleranz, aber auch Intoleranzen gegen Weizen spielen eine zunehmende Rolle. Die Diagnostik von NMI erfordert eine umfangreiche Ausschlussdiagnostik, wobei insbesondere das Reizdarmsyndrom und die intestinale Dysbiose abgegrenzt werden müssen. Die Therapie der NMI basiert primär auf einer gezielten Eliminationsdiät. Im vorliegenden Fortbildungsbeitrag wird auf die wichtigsten NMI eingegangen.
    • Publication Date:
      Date Created: 20220209 Date Completed: 20220302 Latest Revision: 20220302
    • Publication Date:
      20220307
    • Accession Number:
      10.1007/s00108-021-01257-w
    • Accession Number:
      35138431